Biote
Biote Nutraceuticals - Methyl Factors+ - Circulation + Mood (90 Capsules)
Biote Nutraceuticals - Methyl Factors+ - Circulation + Mood (90 Capsules)
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Five active methylation nutrients for heart, mood and detox support, in one daily serving.*
Biote Methyl Factors+ delivers 5-MTHF (methylfolate), vitamin B6 as P-5-P, vitamin B2 as riboflavin 5'-phosphate, vitamin B12 as methylcobalamin and betaine. Every nutrient comes in its active, ready-to-use form, so your body doesn't need to convert it first. Together they support methylation and help maintain healthy homocysteine levels, a key marker of cardiovascular health.*
Who it's for
- Adults who want to support healthy homocysteine levels and heart health*
- People with common MTHFR gene variations who do better with methylfolate than folic acid
- Anyone following a Biote hormone optimization plan, where it's often paired with DIM SGS+ and ADK
- People looking for support for mood, focus and steady energy*
- Anyone whose diet is heavy in processed foods, which are low in these nutrients
How methylation works
Methylation is a chemical process that happens billions of times a day in nearly every cell. It helps regulate your cardiovascular, nervous, reproductive and detoxification systems.* Folate, B6, B12, B2 and betaine work as a team to recycle homocysteine into methionine, an amino acid your body uses to make SAMe, its main methyl donor. When these nutrients run low, homocysteine can build up. Healthy homocysteine levels are linked with heart, bone, cognitive and reproductive health.*
Why the active forms matter
Standard folic acid and cyanocobalamin have to be converted before your body can use them. Many people carry MTHFR variations that slow that conversion. Methyl Factors+ skips the step: folate comes as L-5-MTHF and B12 as methylcobalamin, both already in their active forms.*
Ingredient spotlight
- Folate (as L-5-MTHF): the active form of folate and a direct methyl donor, used to recycle homocysteine and make neurotransmitters such as serotonin and dopamine.*
- Vitamin B12 (as methylcobalamin): works with folate to convert homocysteine to methionine and supports energy and nerve health.*
- Vitamin B6 (as pyridoxal 5'-phosphate): the active form of B6, which helps clear homocysteine through a second pathway and supports neurotransmitter production.*
- Vitamin B2 (as riboflavin 5'-phosphate): the active form of riboflavin, needed to keep the folate cycle running.*
- Betaine (trimethylglycine, TMG): donates methyl groups through a separate pathway to support healthy homocysteine levels and liver function.*
Why customers choose it
- All five nutrients in active, bioavailable forms
- 5,000 mcg DFE methylfolate and 3,000 mcg methyl B12 per serving
- 1.8 g betaine (TMG) for extra methylation support
- Free of gluten, dairy and soy
- 90 capsules, a 30-day supply
What's inside (per 3 capsules)
Riboflavin (vitamin B2, as riboflavin 5'-phosphate sodium) 90 mg, vitamin B6 (as pyridoxal 5'-phosphate) 45 mg, folate 5,000 mcg DFE (3,000 mcg as L-5-methyltetrahydrofolic acid, glucosamine salt), vitamin B12 (as methylcobalamin) 3,000 mcg, betaine anhydrous (trimethylglycine) 1.8 g.
Other ingredients: hypromellose capsule (derived from cellulose), calcium citrate, calcium laurate.
Suggested use
Take 3 capsules daily with water, or as directed by your health care practitioner.
Caution: Not intended for children under 18 or for women who are pregnant or nursing. Consult your physician before use if you have a medical condition or take medication.
Good to know: riboflavin (B2) can turn urine bright yellow. That's normal and harmless.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
